Best Mattress 2025 For Back Pain Relief. Sufferers of degenerative disc disease will find that this mattress provides sufficient relief from back pain. Can a new mattress completely cure.

Unflagging support, a medium firmness. We chose the helix midnight luxe with ergoalign as our best overall mattress for back pain because it offers a balanced amount of support and pressure relief in most sleep positions to help distribute weight away from.